sexualityandu.ca - Your Link to Sexual Well-Being
Home About Us Media Room E-Bulletin Multimedia FAQs Français
Teens Adults Parents Teachers Health Professionals
Health Professionals

How to Choose the Right Contraceptive Method

How They Work; Pros and Cons

Intra-uterine System (Mirena®)

Composition

A small polyethylene T-shaped frame.  The stem of the T has a cylindrical reservoir that contains levonorgestrel.  The cylinder slowly releases the hormone through a rate-limiting membrane.

Mechanism of Action The IUS produces a weak foreign body reaction and endometrial changes that include endometrial decidualization and glandular atrophy.  Cervical mucus may become thicker which creates a barrier to sperm penetration.  Ovulation may be inhibited in some women.
Dosage

The Mirena IUS is available in only one dosage of levonorgestrel.  It is effective for up to five years.  The IUS can be inserted at any time during the menstrual cycle once pregnancy or the possibility of pregnancy has been ruled out.  Insertion may be easier at the time of menstruation, or 3-4 hours after the vaginal insertion of 400 mcg of misoprostol.  It is effective immediately. 

Advantages
  1. Reversible, private, and coitally independent method of contraception..
  2. Less adherence demanding
  3. May be used by women who have contraindications or sensitivity to estrogen, for example women over age 35 who smoke.
  4. May be used by breastfeeding mothers.
  5. May be used for family spacing or in women considering long term contraception.
  6. May be used in women with menorrhagia, dysfunctional uterine bleeding, or perimenopausal menstrual irregularity, provided pathology has been ruled out.  IUS users experience a significant reduction in menstrual bleeding and may even become amenorrheic.
  7. May be considered in special needs patients who need long term assistance with menstrual management.
Disadvantages/Side Effects-
  1. Perforation at the time of insertion.  Incidence of perforation is 0.6 to 1.6 per 1000 insertions.
  2. Infection may occur at the time of insertion.
  3. Expulsion may occur .  This is most common in the first year of use.  The 5 year cumulative expulsion rate for the IUS is about 6%.
  4. Irregular menstrual bleeding or spotting may occur, more often in the first 4-6 months of use.  This usually improves after that time.
  5. The IUS does not increase the risk of ectopic pregnancy.  However, if a woman were to become pregnant with an IUS in place, there is an increased risk that this will be an ectopic pregnancy. 
Efficacy- The Mirena IUS is an extremely effective method of contraception.  The Pearl Index is 0.09 (number of failures per 100 women years of use).
Contraindications/Poor Candidates-

Absolute

  1. Current or recurrent Pelvic Inflammatory Disease or STI
  2. Known or suspected pregnancy
  3. Immediately post septic abortion
  4. Severely distorted uterine cavity
  5. Known allergy to any component of the device
  6. Undiagnosed irregular genital tract bleeding
  7. Malignant trophoblastic disease, breast, cervical or endometrial cancer

Relative

  1. Very high individual likelihood of exposure to gonorrhea or Chlamydia
  2. <48 hours to <4 weeks post-partum
  3. Benign gestational trophoblastic disease
  4. IUS users with AIDS should be closely monitored for pelvic infection.
Follow-up One to three months after insertion to review satisfaction, side effects, and to reinforce the issue of condom use for protection against STIs and HIV.  The IUS user should be instructed to contact a health care provider if any of the following occur: she cannot feel the IUS threads; she or her partner can feel the lower end of the IUS; she thinks she is pregnant; she experiences persistent abdominal pain, fever or unusual vaginal discharge; she or her partner fell pain during intercourse; she wishes to have the device removed or she wishes to conceive.

Last Modified: November 6, 2007



E-Bulletin - Latest Edition
Condom - Application Demo
SEX-FU Challenge
hpvinfo.ca